SCHEMBL1789018

SCHEMBL1789018

CC(C)(C)OC(=O)Oc1cccc(F)c1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.51
ESR1 P03372 1/20 0.49
ESR2 Q92731 1/20 0.49
CYP3A4 P08684 1/20 0.42
CA2 P00918 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
PARP1 P09874 1/20 0.41
HPGD P15428 2/20 0.40
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
MRGPRX4 Q96LA9 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
ALDH1A1 P00352 2/20 0.39
KDM1A O60341 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1789548 0.84 ESR1 (0.44) ELANEESR1ESR2CYP3A4NPC1
SCHEMBL5487011 0.84 ESR1 (0.54) ESR1ESR2CYP3A4NPC1RAB9A
SCHEMBL6392035 0.83 CYP3A4 (0.62) ELANEESR1ESR2CYP3A4CA2
SCHEMBL1789411 0.82 ELANE (0.53) ELANECA2CES2CES1KDM1A
SCHEMBL1789019 0.82 ESR1 (0.43) ESR1ESR2CYP3A4NPC1RAB9A
SCHEMBL2738445 0.81 LMNA (0.61) ELANECYP3A4PPARGMEN1KMT2A
SCHEMBL12315891 0.81 ELANE (0.53) ELANEESR1ESR2CYP3A4CA2
SCHEMBL7543464 0.81 NPC1 (0.51) ESR1ESR2NPC1RAB9AHPGD
SCHEMBL10757686 0.81 ATM (0.51) ELANEPPARGPPARAMRGPRX4CES2
SCHEMBL13778256 0.81 ENPP2 (0.53) ELANECYP3A4CA2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2249426-B1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY MITSUBISHI CHEM CORP (JP) 2019-07-10 EP disclosed
US-9083058-B2 Nonaqueous electrolytic solution and nonaqueous-electrolyte battery MITSUBISHI CHEMICAL CORPORATION (JP) 2015-07-14 US disclosed
US-8916298-B2 Nonaqueous electrolytic solution and nonaqueous-electrolyte battery MITSUBISHI CHEMICAL CORPORATION (JP) 2014-12-23 US disclosed
US-8889302-B2 Nonaqueous electrolytic solution and nonaqueous-electrolyte battery MITSUBISHI CHEMICAL CORPORATION (JP) 2014-11-18 US disclosed
US-8846254-B2 2014-09-30 US disclosed
US-20140134481-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2014-05-15 US disclosed
US-20120308883-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-12-06 US disclosed
US-20120219854-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-30 US disclosed
US-20110123871-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY MITSUBISHI CHEMCIAL (JP) 2011-05-26 US disclosed
EP-2249426-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY Mitsubishi Chemical Corporation (JP) 2010-11-10 EP disclosed