Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 15/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | F9 | P00740 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | F12 | P00748 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | F7 | P08709 | 2/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27385409 | 0.87 | F2 (0.36) | P2RX7RAB9AF2F9F10 | |
| SCHEMBL27385046 | 0.82 | RAB9A (0.46) | P2RX7RAB9ASMN1; SMN2 | |
| SCHEMBL27385173 | 0.81 | SLC6A2 (0.39) | P2RX7RAB9AF2SMN1; SMN2 | |
| SCHEMBL27384658 | 0.80 | HTT (0.46) | SMN1; SMN2 | |
| SCHEMBL30920785 | 0.79 | RAB9A (0.39) | RAB9A | |
| SCHEMBL27383947 | 0.78 | RAB9A (0.55) | P2RX7RAB9ASMN1; SMN2 | |
| SCHEMBL27383268 | 0.76 | RAB9A (0.61) | RAB9ASMN1; SMN2 | |
| SCHEMBL27385168 | 0.75 | RAB9A (0.47) | P2RX7RAB9ASMN1; SMN2 | |
| SCHEMBL27384652 | 0.74 | SMN1; SMN2 (0.41) | RAB9ASMN1; SMN2 | |
| SCHEMBL27382489 | 0.74 | SMN1; SMN2 (0.47) | RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081748-A2 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2024-04-18 | — | — | WO | disclosed |