Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27382975 | 0.83 | CACNA1G (0.48) | SMN1; SMN2RAB9AMAPTMEN1LMNA | |
| SCHEMBL27384177 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2RAB9AMAPTMEN1LMNA | |
| SCHEMBL27384105 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9AMAPTMEN1LMNA | |
| SCHEMBL27384649 | 0.79 | HTT (0.42) | SMN1; SMN2RAB9AMAPTMEN1LMNA | |
| SCHEMBL27383346 | 0.78 | RAB9A (0.45) | SMN1; SMN2RAB9AMAPTMEN1LMNA | |
| SCHEMBL27384009 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9AMAPTMEN1LMNA | |
| SCHEMBL30946281 | 0.77 | ALDH1A1 (0.41) | SMN1; SMN2RAB9AMAPTMEN1KMT2A | |
| SCHEMBL27382489 | 0.74 | SMN1; SMN2 (0.47) | SMN1; SMN2RAB9AMAPTMEN1LMNA | |
| SCHEMBL27246881 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2RAB9AMAPTMEN1LMNA | |
| SCHEMBL27382677 | 0.72 | RAB9A (0.48) | SMN1; SMN2RAB9AMAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081748-A2 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2024-04-18 | — | — | WO | disclosed |