Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | DDR2 | Q16832 | 4/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27388126 | 0.87 | PKMYT1 (0.44) | PKMYT1MAPK14ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL27388135 | 0.84 | PKMYT1 (0.37) | PKMYT1MAPK14ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL27387961 | 0.81 | PKMYT1 (0.36) | PKMYT1MAPK14ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL30971143 | 0.81 | PKMYT1 (0.36) | PKMYT1MAPK14ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL27387956 | 0.73 | PKMYT1 (0.44) | PKMYT1ALDH1A1MAPTHTTFGFR1 | |
| SCHEMBL30971122 | 0.73 | PKMYT1 (0.44) | PKMYT1ALDH1A1MAPTHTTFGFR1 | |
| SCHEMBL30971268 | 0.73 | ACACB (0.38) | PKMYT1MAPK14ALDH1A1MAPTHTT | |
| SCHEMBL27387965 | 0.70 | PKMYT1 (0.36) | PKMYT1ALDH1A1MAPTHTTFGFR1 | |
| SCHEMBL30971103 | 0.68 | CYP1A2 (0.35) | ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL24785041 | 0.66 | MAOB (0.40) | BRD4MAOBFGFR1ROCK2PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |