Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | LTK | P29376 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27388126 | 0.85 | PKMYT1 (0.44) | ARCHEK1BTKPLK4AURKA | |
| SCHEMBL30971043 | 0.81 | GRM2 (0.42) | KDM4EPKMYT1 | |
| SCHEMBL30971255 | 0.76 | AR (0.38) | SYKARKDM4ECHEK1CHEK2 | |
| SCHEMBL30971258 | 0.76 | UCHL3 (0.34) | SYKKDM4EMAPTALDH1A1MAPK1 | |
| SCHEMBL27402209 | 0.75 | MAPT (0.44) | SYKKDM4EMKNK1MKNK2MAPT | |
| SCHEMBL30971103 | 0.74 | CYP1A2 (0.35) | MAPTHPGDSALDH1A1MAOB | |
| SCHEMBL27388135 | 0.73 | PKMYT1 (0.37) | ACACBFGFR1ROCK1LRRK2MAPT | |
| SCHEMBL27388133 | 0.73 | PKMYT1 (0.39) | KDM4EFGFR1LRRK2MAPTALDH1A1 | |
| SCHEMBL30971229 | 0.72 | AR (0.38) | SYKARCHEK1CHEK2MKNK1 | |
| SCHEMBL30971088 | 0.70 | ADORA3 (0.41) | KDM4EMAPTFASNALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638420-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |