Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30971258 | 0.89 | UCHL3 (0.34) | KITGRM2JAK2JAK1TYK2 | |
| SCHEMBL30971043 | 0.88 | GRM2 (0.42) | GRM2 | |
| SCHEMBL30971143 | 0.86 | PKMYT1 (0.36) | CYP1A2BRD4ROCK2PIM1GSK3B | |
| SCHEMBL27387961 | 0.86 | PKMYT1 (0.36) | CYP1A2BRD4ROCK2PIM1GSK3B | |
| SCHEMBL30971088 | 0.76 | ADORA3 (0.41) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL27387956 | 0.74 | PKMYT1 (0.44) | GRM2MAPTALDH1A1 | |
| SCHEMBL30971122 | 0.74 | PKMYT1 (0.44) | GRM2MAPTALDH1A1 | |
| SCHEMBL30971268 | 0.74 | ACACB (0.38) | HPGDSMAOBMAPTALDH1A1 | |
| SCHEMBL27387965 | 0.71 | PKMYT1 (0.36) | GRM2JAK2MAPTALDH1A1MAP4K1 | |
| SCHEMBL27388133 | 0.68 | PKMYT1 (0.39) | CYP1A2BRD4ROCK2PIM1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638420-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |