Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 10/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14746862 | 0.83 | ALDH1A1 (0.54) | KMT2AALDH1A1KDM4EAGTR1RAB9A | |
| SCHEMBL14982070 | 0.79 | ALDH1A1 (0.51) | KMT2AALDH1A1KDM4EAGTR1RAB9A | |
| SCHEMBL13232107 | 0.79 | ALDH1A1 (0.62) | KMT2AALDH1A1KDM4EPPARG | |
| SCHEMBL1532856 | 0.79 | KMT2A (0.58) | KMT2AALDH1A1KDM4EAGTR1RAB9A | |
| SCHEMBL11265463 | 0.79 | ALDH1A1 (0.57) | KMT2AALDH1A1KDM4EAGTR1RAB9A | |
| SCHEMBL11275701 | 0.78 | ALDH1A1 (0.49) | KMT2AALDH1A1KDM4EAGTR1RAB9A | |
| SCHEMBL8585150 | 0.76 | KMT2A (0.59) | KMT2AALDH1A1KDM4EAGTR1RAB9A | |
| SCHEMBL10864406 | 0.76 | KMT2A (0.55) | KMT2AALDH1A1PPARGAKR1C3 | |
| SCHEMBL2588918 | 0.76 | KMT2A (0.55) | KMT2AALDH1A1PPARGAKR1C3 | |
| SCHEMBL698881 | 0.76 | AGTR1 (0.60) | KMT2AALDH1A1KDM4EAGTR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1093124-C | Substituted 4-hydroxy-phenylalcanoic acid derivatives with activity to ppar-'gamma' | GLAXO GROUP LTD (GB) | 2002-10-23 | — | — | CN | disclosed |
| CN-1218460-A | Substituted 4-hydroxy-phenylalcanoic acid derivatives with activity to ppar-'gamma' | GLAXO GROUP LTD (GB) | 1999-06-02 | — | — | CN | disclosed |