Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12031931 | 0.82 | DRD2 (0.50) | HTR3ADRD2CYP2C9LSS | |
| SCHEMBL10177557 | 0.78 | DRD2 (0.49) | HTR3ADRD2ESR2CYP2C9LSS | |
| SCHEMBL15627273 | 0.76 | CNR2 (0.42) | HTR3ADRD2ESR2LSSKDM1A | |
| SCHEMBL27393727 | 0.76 | SLC2A1 (0.39) | HTR3ADRD2ESR2CYP2C9LSS | |
| SCHEMBL10177748 | 0.75 | HTR2A (0.49) | HTR3ADRD2ESR2CYP2C9HTR2A | |
| SCHEMBL10692927 | 0.75 | ESR2 (0.55) | HTR3ADRD2ESR2CYP2C9IDO1 | |
| SCHEMBL8025867 | 0.75 | CYP2C9 (0.59) | HTR3ADRD2ESR2CYP2C9LSS | |
| SCHEMBL260852 | 0.75 | CYP2C9 (0.59) | HTR3ADRD2ESR2CYP2C9LSS | |
| SCHEMBL6451898 | 0.74 | DRD2 (0.45) | HTR3ADRD2CYP2C9LSSIDO1 | |
| SCHEMBL6451902 | 0.74 | DRD2 (0.45) | HTR3ADRD2CYP2C9LSSIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024108198-A2 | METHODS OF TREATING OBESITY WITH AN MC4R AGONIST | RHYTHM PHARMACEUTICALS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |