Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSPO | P30536 | 2/20 | 0.41 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.39 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.39 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14925281 | 0.86 | KMT2A (0.46) | ALDH1A1HTTTSHRKMT2AMEN1 | |
| SCHEMBL5688285 | 0.80 | ALDH1A1 (0.41) | ALDH1A1HTTMAPK1CYP3A4HPGD | |
| SCHEMBL26032149 | 0.78 | POLB (0.48) | CYP2C9ALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL24834354 | 0.78 | CYP2C9 (0.37) | CYP2C9ALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL6074176 | 0.78 | MAPT (0.51) | ALDH1A1HTTMAPK1CYP3A4HPGD | |
| SCHEMBL11135619 | 0.77 | CA12 (0.42) | CYP2C9ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL9396479 | 0.76 | POLB (0.46) | ALDH1A1KMT2AMEN1MAPK1HPGD | |
| SCHEMBL11208904 | 0.74 | CYP2C9 (0.40) | CYP2C9ALDH1A1HTTTSHRKMT2A | |
| SCHEMBL14662766 | 0.73 | POLB (0.42) | CYP2C9ALDH1A1HTTMAPK1CYP3A4 | |
| SCHEMBL9396448 | 0.73 | POLB (0.55) | ALDH1A1KMT2AMEN1MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024121259-A1 | TARGETED PROTEIN DEGRADATION USING PRODRUGS OF BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2024-06-13 | — | — | WO | disclosed |