SCHEMBL5688285

SCHEMBL5688285

COc1ccc([Te][Te]c2ccc(OC)cc2N(C)C(C)=O)c(N(C)C(C)=O)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.41
▸ HTT P42858 1/20 0.41
▸ CYP3A4 P08684 3/20 0.40
▸ HPGD P15428 1/20 0.40
▸ MAPK1 P28482 1/20 0.40
▸ TSPO P30536 2/20 0.40
▸ FSCN1 Q16658 1/20 0.39
▸ NPC1 O15118 2/20 0.38
▸ RAB9A P51151 2/20 0.38
▸ HSD17B1 P14061 1/20 0.38
▸ HSD17B2 P37059 1/20 0.38
▸ MTNR1A P48039 2/20 0.37
▸ MTNR1B P49286 2/20 0.37
▸ KDM4E B2RXH2 2/20 0.37
▸ CYP1A2 P05177 2/20 0.36
▸ CYP2C19 P33261 1/20 0.36
▸ LMNA P02545 2/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ SMN1; SMN2 Q16637 2/20 0.36
▸ TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27393718 0.80 CYP2C9 (0.44) ALDH1A1HTTCYP3A4HPGDMAPK1
SCHEMBL14925281 0.77 KMT2A (0.46) ALDH1A1HTTCYP3A4HPGDMAPK1
SCHEMBL6074176 0.75 MAPT (0.51) ALDH1A1HTTCYP3A4HPGDMAPK1
SCHEMBL9396479 0.74 POLB (0.46) ALDH1A1HPGDMAPK1NPC1RAB9A
SCHEMBL9795749 0.72 TSPO (0.50) ALDH1A1TSPOFSCN1NPC1RAB9A
SCHEMBL9396448 0.71 POLB (0.55) ALDH1A1HPGDMAPK1NPC1RAB9A
SCHEMBL5685396 0.70 FSCN1 (0.41) ALDH1A1TSPOFSCN1RAB9ASMN1; SMN2
SCHEMBL2537515 0.70 ALDH1A1 (0.71) ALDH1A1HTTCYP3A4MAPK1NPC1
SCHEMBL11744036 0.69 NPSR1 (0.46) ALDH1A1HTTCYP3A4CYP1A2CYP2C19
SCHEMBL9795882 0.69 HTT (0.52) ALDH1A1HTTCYP3A4MAPK1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718679-B1 Cubical silver iodochloride emulsions, processes for their preparation and photographic print elements EASTMAN KODAK CO (US) 2006-02-15 — — EP disclosed
EP-0772079-B1 Light-sensitive silber halide emulsions and processes for their preparation EASTMAN KODAK CO (US) 2002-12-11 — — EP disclosed
EP-0772079-A2 Light-sensitive silber halide emulsions and processes for their preparation EASTMAN KODAK COMPANY (US) 1997-05-07 — — EP disclosed
EP-0718679-A1 Cubical silver iodochloride emulsions, processes for their preparation and photographic print elements EASTMAN KODAK COMPANY (US) 1996-06-26 — — EP disclosed
EP-0718676-A1 Photographic print elements containing emulsions of enhanced speed and controlled minimum densities EASTMAN KODAK COMPANY (US) 1996-06-26 — — EP disclosed
EP-0617320-A2 Tabular grain emulsions containing antifoggants and stabilizers EASTMAN KODAK COMPANY (US) 1994-09-28 — — EP disclosed
US-5320938-A Occurs in the presence of iodide EASTMAN KODAK COMPANY (US) 1994-06-14 — — US disclosed
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