Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.63 |
| ▸ | ACE | P12821 | 4/20 | 0.57 |
| ▸ | CPA1 | P15085 | 4/20 | 0.57 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.57 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | XIAP | P98170 | 1/20 | 0.54 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2740200 | 1.00 | MME (0.63) | MMEACECPA1ACE2ALPI | |
| SCHEMBL2739525 | 1.00 | MME (0.63) | MMEACECPA1ACE2ALPI | |
| SCHEMBL2739563 | 1.00 | MME (0.63) | MMEACECPA1ACE2ALPI | |
| Trifluoroacetic Acid SCHEMBL29484056 | 0.93 | MME (0.56) | MMEACECPA1ACE2NPSR1 | |
| SCHEMBL30581391 | 0.90 | MME (0.67) | MMEACECPA1ACE2ALPI | |
| SCHEMBL1329567 | 0.90 | MME (0.67) | MMEACECPA1ACE2ALPI | |
| SCHEMBL825577 | 0.90 | MME (0.67) | MMEACECPA1ACE2ALPI | |
| SCHEMBL5065345 | 0.90 | MME (0.67) | MMEACECPA1ACE2ALPI | |
| SCHEMBL30581399 | 0.90 | MME (0.67) | MMEACECPA1ACE2ALPI | |
| SCHEMBL7355800 | 0.90 | MME (0.67) | MMEACECPA1ACE2ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9512176-B2 | Age inhibitors | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2016-12-06 | — | — | US | disclosed |
| US-20120252866-A1 | Age Inhibitors | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2012-10-04 | — | — | US | disclosed |
| EP-1863832-B1 | AGE INHIBITORS | CENTRE NAT RECH SCIENT (FR) | 2012-01-04 | — | — | EP | disclosed |
| US-20080249030-A1 | Age Inhibitors | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2008-10-09 | — | — | US | disclosed |
| US-20080249030-A1 | Age Inhibitors | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2008-10-09 | — | — | US | disclosed |
| WO-2006103274-A9 | AGE INHIBITORS | PHARMAMENS (FR) | 2007-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252866-A1 | Age Inhibitors | CFH, CDKL1, XPNPEP1 | MME 656/4885ACE 253/4885CPA1 6/4885 |
| US-20080249030-A1 | Age Inhibitors | CFH, XPA, XPNPEP1 | MME 909/4885ACE 587/4885CPA1 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.