Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.63 |
| ▸ | ACE | P12821 | 4/20 | 0.57 |
| ▸ | CPA1 | P15085 | 4/20 | 0.57 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.57 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | XIAP | P98170 | 1/20 | 0.54 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2739525 | 1.00 | MME (0.63) | MMEACECPA1ACE2ALPI | |
| SCHEMBL2739563 | 1.00 | MME (0.63) | MMEACECPA1ACE2ALPI | |
| SCHEMBL2739487 | 1.00 | MME (0.63) | MMEACECPA1ACE2ALPI | |
| Trifluoroacetic Acid SCHEMBL29484056 | 0.93 | MME (0.56) | MMEACECPA1ACE2NPSR1 | |
| SCHEMBL30581391 | 0.90 | MME (0.67) | MMEACECPA1ACE2ALPI | |
| SCHEMBL1329567 | 0.90 | MME (0.67) | MMEACECPA1ACE2ALPI | |
| SCHEMBL825577 | 0.90 | MME (0.67) | MMEACECPA1ACE2ALPI | |
| SCHEMBL5065345 | 0.90 | MME (0.67) | MMEACECPA1ACE2ALPI | |
| SCHEMBL30581399 | 0.90 | MME (0.67) | MMEACECPA1ACE2ALPI | |
| SCHEMBL7355800 | 0.90 | MME (0.67) | MMEACECPA1ACE2ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863832-B1 | AGE INHIBITORS | CENTRE NAT RECH SCIENT (FR) | 2012-01-04 | — | — | EP | disclosed |