Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL29484056

NC[C@H](N)C(=O)N[C@@H](Cc1ccccc1)C(=O)O.O=C(O)C(F)(F)F

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 4/20 0.56
▸ ACE P12821 5/20 0.52
▸ CPA1 P15085 3/20 0.51
▸ ACE2 Q9BYF1 3/20 0.51
▸ NPSR1 Q6W5P4 1/20 0.51
▸ FPR2 P25090 1/20 0.50
▸ ECE1 P42892 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2740200 0.93 MME (0.63) MMEACECPA1ACE2NPSR1
SCHEMBL2739563 0.93 MME (0.63) MMEACECPA1ACE2NPSR1
SCHEMBL2739487 0.93 MME (0.63) MMEACECPA1ACE2NPSR1
SCHEMBL2739525 0.93 MME (0.63) MMEACECPA1ACE2NPSR1
Trifluoroacetic Acid SCHEMBL29484059 0.91 PTPN1 (0.52) —
Trifluoroacetic Acid SCHEMBL29484051 0.87 ALDH1A1 (0.58) —
Trifluoroacetic Acid SCHEMBL29617362 0.86 NAALAD2 (0.60) MMEACE
SCHEMBL2739560 0.85 FPR2 (0.55) MMEACECPA1ACE2NPSR1
SCHEMBL825577 0.84 MME (0.67) MMEACECPA1ACE2NPSR1
SCHEMBL1329567 0.84 MME (0.67) MMEACECPA1ACE2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612429-B2 Derivatives of dolaproine-dolaisoleuine peptides AGENSYS, INC. (US) 2026-04-28 — — US disclosed
US-20220204557-A1 DERIVATIVES OF DOLAPROINE-DOLAISOLEUINE PEPTIDES AGENSYS, INC. (US) 2022-06-30 — — US disclosed
US-11312748-B2 Derivatives of dolaproine-dolaisoleucine peptides AGENSYS, INC. (US) 2022-04-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220204557-A1 DERIVATIVES OF DOLAPROINE-DOLAISOLEUINE PEPTIDES DDOST, VIP, THPO MME 1043/4885ACE 1764/4885CPA1 941/4885
US-12612429-B2 Derivatives of dolaproine-dolaisoleuine peptides DDOST, NGLY1, GRPR MME 969/4885ACE 2286/4885CPA1 156/4885
US-11312748-B2 Derivatives of dolaproine-dolaisoleucine peptides VIP, DDOST, DNPEP MME 541/4885ACE 1878/4885CPA1 526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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