Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | AKT2 | P31751 | 1/20 | 0.43 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27397727 | 0.87 | KDM4E (0.40) | IKBKBCHUKAKT1AKT2AKT3 | |
| SCHEMBL27418174 | 0.86 | HDAC6 (0.55) | HDAC6MAPTKDM4ELMNAKMT2A | |
| SCHEMBL27396160 | 0.82 | RET (0.43) | HDAC6MAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL8784898 | 0.78 | CSF1R (0.62) | IKBKBCHUKAKT1AKT2AKT3 | |
| SCHEMBL8784716 | 0.77 | IKBKB (0.55) | DPP4IKBKBCHUKAKT1AKT2 | |
| SCHEMBL8786834 | 0.77 | KDM4E (0.57) | DPP4IKBKBCHUKAKT1AKT2 | |
| SCHEMBL8785545 | 0.76 | DPP4 (0.51) | DPP4IKBKBCHUKAKT1AKT2 | |
| SCHEMBL9236400 | 0.76 | ACLY (0.47) | DPP4IKBKBCHUKAKT1AKT2 | |
| SCHEMBL19925264 | 0.74 | DPP4 (0.51) | DPP4IKBKBCHUKAKT1AKT2 | |
| SCHEMBL9588260 | 0.74 | KDM4E (0.59) | KDM4ELMNAKMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1090274-A | Condensed heterocyclic compounds and its preparation method and application | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-08-03 | — | — | CN | disclosed |