Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.39 |
| ▸ | WEE1 | P30291 | 3/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27394945 | 0.87 | DPP4 (0.46) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL8784656 | 0.79 | ALDH1A1 (0.54) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL8544707 | 0.78 | KMT2A (0.47) | KDM4ECHEK1WEE1DNMT1SMN1; SMN2 | |
| SCHEMBL8543014 | 0.76 | KDM4E (0.44) | KDM4EALDH1A1GAAHPGDCHEK1 | |
| SCHEMBL27418174 | 0.75 | HDAC6 (0.55) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL9588260 | 0.72 | KDM4E (0.59) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL8543548 | 0.71 | CHEK1 (0.40) | KDM4EALDH1A1GAAHPGDCHEK1 | |
| SCHEMBL9359224 | 0.70 | ALDH1A1 (0.54) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL24893025 | 0.70 | ABCB11 (0.51) | KDM4EALDH1A1GAAHPGDKMT2A | |
| SCHEMBL9358757 | 0.70 | EDNRB (0.42) | KDM4EALDH1A1GAAHPGDCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1090274-A | Condensed heterocyclic compounds and its preparation method and application | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-08-03 | — | — | CN | disclosed |