Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 4/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27418174 | 0.83 | HDAC6 (0.55) | HDAC6LMNAKMT2ASMN1; SMN2MAPT | |
| SCHEMBL27394945 | 0.82 | DPP4 (0.46) | HDAC6LMNAKMT2ASMN1; SMN2MAPT | |
| SCHEMBL8784910 | 0.78 | TSHR (0.56) | LMNAKMT2ASMN1; SMN2MAPTPADI4 | |
| SCHEMBL9588260 | 0.72 | KDM4E (0.59) | LMNAKMT2ASMN1; SMN2TSHR | |
| SCHEMBL4766620 | 0.70 | EDNRB (0.51) | TACR1KMT2AMAPTTSHREDNRB | |
| SCHEMBL27397727 | 0.70 | KDM4E (0.40) | LMNAKMT2ASMN1; SMN2MAPTTP53 | |
| SCHEMBL19661320 | 0.70 | TSHR (0.44) | LMNASMN1; SMN2MAPTTP53TSHR | |
| SCHEMBL4764285 | 0.69 | EDNRB (0.53) | KMT2AMAPTTP53TSHRPDE10A | |
| SCHEMBL10490954 | 0.67 | KMT2A (0.40) | LMNAKMT2ASMN1; SMN2MAPTTP53 | |
| SCHEMBL9628751 | 0.66 | MEN1 (0.42) | LMNAKMT2ASMN1; SMN2MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1090274-A | Condensed heterocyclic compounds and its preparation method and application | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-08-03 | — | — | CN | disclosed |