Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22785953 | 0.88 | TSHR (0.47) | TSHRTHRBALDH1A1 | |
| SCHEMBL12793084 | 0.84 | TSHR (0.47) | TSHRTHRBPRKCAALDH1A1 | |
| SCHEMBL12793095 | 0.83 | TSHR (0.46) | TSHRTHRBPRKCAALDH1A1 | |
| SCHEMBL279041 | 0.83 | TSHR (0.49) | TSHRTHRBPRKCAHMGCRALDH1A1 | |
| SCHEMBL16864561 | 0.80 | TSHR (0.39) | TSHRTHRBPRKCA | |
| SCHEMBL11046041 | 0.79 | TSHR (0.61) | TSHRTHRBALDH1A1 | |
| SCHEMBL539233 | 0.79 | TSHR (0.61) | TSHRTHRBALDH1A1 | |
| SCHEMBL13309525 | 0.79 | TSHR (0.53) | TSHRTHRBPRKCAALDH1A1 | |
| SCHEMBL16865723 | 0.78 | THRB (0.41) | TSHRTHRBHMGCRALDH1A1 | |
| SCHEMBL12793091 | 0.78 | TSHR (0.34) | TSHRPRKCAHMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088552-B2 | Photosensitive composition and lithographic printing original plate using the composition | OKAMOTO CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-01-03 | — | — | US | disclosed |
| US-20090208870-A1 | Photosensitive composition and lithographic printing original plate using the composition | OKAMOTO CHEMICAL INDUSTRY CO.,LTD. | 2009-08-20 | — | — | US | disclosed |