Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27398528 | 0.85 | KCNN4 (0.36) | SMN1; SMN2POLBAOX1MAPTALDH1A1 | |
| SCHEMBL27602915 | 0.75 | PIN1 (0.43) | SMN1; SMN2PIN1POLBMMP8ATM | |
| SCHEMBL27535328 | 0.75 | KCNN4 (0.36) | SMN1; SMN2MAPTALDH1A1CACNA1GLMNA | |
| SCHEMBL21119495 | 0.74 | PIN1 (0.42) | SMN1; SMN2PIN1POLBMMP8ATM | |
| SCHEMBL21119496 | 0.73 | PIN1 (0.41) | SMN1; SMN2PIN1POLBMMP8MAPT | |
| SCHEMBL11578597 | 0.73 | SMN1; SMN2 (0.49) | SMN1; SMN2PIN1POLBMMP8ATM | |
| SCHEMBL2352709 | 0.69 | ALDH1A1 (0.51) | SMN1; SMN2PIN1POLBMMP8ALDH1A1 | |
| SCHEMBL8796326 | 0.69 | SMN1; SMN2 (0.46) | SMN1; SMN2PIN1POLBMMP8ATM | |
| SCHEMBL8767191 | 0.69 | SMN1; SMN2 (0.51) | SMN1; SMN2PIN1POLBMMP8ATM | |
| SCHEMBL10577078 | 0.68 | PIN1 (0.47) | SMN1; SMN2PIN1POLBMMP8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1086218-A | Anti-inflammatory agent phosphine acyl acetic acid ester and acid | UPJOHN CO (US) | 1994-05-04 | — | — | CN | claimed |