Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27602915 | 0.79 | PIN1 (0.43) | PIN1ALDH1A1TSHRRECQLMMP8 | |
| SCHEMBL4640323 | 0.78 | CHRM2 (0.48) | PIN1ALDH1A1TSHRRECQLMMP8 | |
| SCHEMBL8482340 | 0.77 | SCN1A (0.51) | PIN1ALDH1A1TSHRRECQLMMP8 | |
| SCHEMBL8483586 | 0.77 | PIN1 (0.53) | PIN1ALDH1A1TSHRRECQLMMP8 | |
| SCHEMBL21119496 | 0.77 | PIN1 (0.41) | PIN1ALDH1A1TSHRRECQLMMP8 | |
| Ammonia Solution, Strong SCHEMBL10879989 | 0.76 | PIN1 (0.51) | PIN1ALDH1A1TSHRRECQLMMP8 | |
| SCHEMBL27636591 | 0.74 | LMNA (0.43) | ALDH1A1MEN1KMT2ALMNANPSR1 | |
| SCHEMBL27397232 | 0.74 | SMN1; SMN2 (0.39) | PIN1ALDH1A1RECQLMMP8MEN1 | |
| SCHEMBL14380533 | 0.74 | SCN1A (0.48) | PIN1ALDH1A1TSHRRECQLMMP8 | |
| SCHEMBL19066561 | 0.74 | MEN1 (0.48) | PIN1ALDH1A1TSHRRECQLMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10336678-B2 | Compositions and methods for preparing β,γ-unsaturated acids | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10336678-B2 | Compositions and methods for preparing β,γ-unsaturated acids | ELOVL5, FASN, ACSL5 | PIN1 429/4885ALDH1A1 239/4885TSHR 4005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.