Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 5/20 | 0.44 |
| ▸ | CCKAR | P32238 | 3/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27461327 | 0.84 | HDAC3 (0.49) | HDAC3HDAC1HDAC8HDAC6HDAC4 | |
| SCHEMBL27374393 | 0.84 | OPRK1 (0.48) | HDAC3HDAC1HDAC8HDAC6HDAC4 | |
| SCHEMBL27534268 | 0.81 | NR1I2 (0.48) | HDAC3HDAC1HDAC8HDAC6HDAC4 | |
| SCHEMBL9088703 | 0.80 | TP53 (0.61) | HDAC3HDAC1HDAC8HDAC6MAPT | |
| SCHEMBL27530023 | 0.79 | CCKBR (0.47) | MAPTALDH1A1TP53CCKBRCCKAR | |
| SCHEMBL27391460 | 0.79 | CCKBR (0.40) | HDAC3HDAC1HDAC8HDAC6MAPT | |
| SCHEMBL27387296 | 0.78 | HDAC3 (0.50) | HDAC3HDAC1HDAC8HDAC6HDAC4 | |
| SCHEMBL9090505 | 0.71 | GABRP (0.54) | MAPTTP53CCKBRCCKARPOLB | |
| SCHEMBL11713523 | 0.70 | HDAC3 (0.60) | HDAC3HDAC1HDAC8HDAC6HDAC4 | |
| SCHEMBL11684214 | 0.69 | HDAC3 (0.46) | HDAC3HDAC1HDAC8HDAC6HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1063103-A | BENZODIAZEPINE DERIVATIVES | YAMANOUCHI PHARMA CO LTD (JP) | 1992-07-29 | — | — | CN | disclosed |