Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL2359755 | 0.78 | NOTUM (0.31) | TDP1LMNA | |
| SCHEMBL29155032 | 0.74 | TSHR (0.43) | TSHRKMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL31396932 | 0.73 | LMNA (0.49) | TSHRKMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL1682492 | 0.71 | ALDH1A1 (0.49) | KMT2AMAPTSMN1; SMN2HPGDMEN1 | |
| SCHEMBL17495602 | 0.71 | KMT2A (0.45) | TSHRKMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL27575996 | 0.71 | KMT2A (0.48) | TSHRKMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL27498398 | 0.70 | KMT2A (0.44) | TSHRKMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL27517794 | 0.70 | KMT2A (0.48) | TSHRKMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL4369600 | 0.69 | LMNA (0.47) | TSHRKMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL30532909 | 0.69 | TSHR (0.53) | TSHRKMT2AMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1064275-A | Imidazopyridines PAF/H1Antagonists | PFIZER (US) | 1992-09-09 | — | — | CN | disclosed |