Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24370438 | 0.88 | TDP1 (0.48) | PLA2G1BATG4BTDP1LMNAKMT2A | |
| SCHEMBL12186155 | 0.80 | KMT2A (0.54) | PLA2G1BATG4BTDP1LMNAKMT2A | |
| SCHEMBL10329767 | 0.80 | SMN1; SMN2 (0.58) | PLA2G1BATG4BTDP1LMNAKMT2A | |
| SCHEMBL26772953 | 0.79 | HRH3 (0.53) | PLA2G1BATG4BTDP1LMNAKMT2A | |
| SCHEMBL19226699 | 0.79 | KMT2A (0.61) | TSHRMGLLLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL19473337 | 0.77 | SMN1; SMN2 (0.65) | TSHRTDP1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL20803928 | 0.77 | SCN9A (0.48) | PLA2G1BATG4BTDP1LMNAKMT2A | |
| SCHEMBL13466364 | 0.75 | PLA2G1B (0.45) | PLA2G1BATG4BTDP1LMNAKMT2A | |
| SCHEMBL23750583 | 0.73 | MKNK1 (0.52) | KMT2AMEN1 | |
| SCHEMBL13466373 | 0.72 | PLA2G1B (0.47) | PLA2G1BATG4BTDP1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097775-A1 | ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS | NUVATION BIO INC. (US) | 2024-05-10 | — | — | WO | disclosed |