Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.54 |
| ▸ | TGFBR1 | P36897 | 12/20 | 0.52 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27399088 | 0.78 | PTGS2 (0.54) | PTGS2TGFBR1TGFBR2 | |
| SCHEMBL1830448 | 0.76 | DYRK1A (0.71) | TGFBR1DYRK1AAKT1PIK3CAMTOR | |
| SCHEMBL27399089 | 0.76 | PTGS2 (0.52) | PTGS2TGFBR1TGFBR2 | |
| SCHEMBL19967375 | 0.74 | PTGS2 (0.67) | PTGS2MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL27399209 | 0.72 | TGFBR1 (0.60) | TGFBR1DYRK1AMAPK14AKT1PIK3CA | |
| SCHEMBL21401310 | 0.71 | TGFBR1 (0.53) | TGFBR1TGFBR2DYRK1AAKT1PIK3CA | |
| SCHEMBL6290575 | 0.70 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL27399097 | 0.70 | TGFBR1 (0.47) | PTGS2TGFBR1DYRK1AAKT1PIK3CA | |
| SCHEMBL27398648 | 0.69 | TGFBR1 (0.43) | TGFBR1DYRK1AAKT1PIK3CAMTOR | |
| SCHEMBL1355263 | 0.69 | DYRK1A (0.53) | TGFBR1DYRK1AAKT1PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024126404-A1 | IMIDAZO[1,2-A]PYRIDINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-20 | — | — | WO | disclosed |