Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.54 |
| ▸ | TGFBR1 | P36897 | 13/20 | 0.42 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27399089 | 0.88 | PTGS2 (0.52) | PTGS2TGFBR1TGFBR2 | |
| SCHEMBL27399082 | 0.78 | PTGS2 (0.54) | PTGS2TGFBR1TGFBR2 | |
| SCHEMBL19967375 | 0.74 | PTGS2 (0.67) | PTGS2 | |
| SCHEMBL27399217 | 0.73 | ADORA2A (0.47) | TGFBR1TGFBR2ADORA2AADORA2BADORA1 | |
| SCHEMBL14041215 | 0.73 | TGFBR1 (0.43) | TGFBR1ADORA2AADORA2BADORA1 | |
| SCHEMBL27399102 | 0.72 | TGFBR1 (0.39) | PTGS2TGFBR1GRM2ADORA2AADORA2B | |
| SCHEMBL27398657 | 0.71 | FLT3 (0.39) | TGFBR1GRM2ADORA2AADORA2BADORA1 | |
| SCHEMBL6290575 | 0.70 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL24155891 | 0.68 | ADORA2A (0.44) | TGFBR1ADORA2AADORA2BADORA1 | |
| SCHEMBL27399170 | 0.68 | TGFBR1 (0.43) | TGFBR1ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024126404-A1 | IMIDAZO[1,2-A]PYRIDINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-20 | — | — | WO | disclosed |