Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.34 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29260330 | 0.83 | CYP17A1 (0.35) | ALDH1A1GAAL3MBTL1KCNQ4KCNQ5 | |
| SCHEMBL23289646 | 0.79 | LMNA (0.37) | ALDH1A1GAAL3MBTL1KCNQ4KCNQ5 | |
| SCHEMBL24255781 | 0.79 | AR (0.33) | ALDH1A1GAAL3MBTL1KCNQ4KCNQ5 | |
| SCHEMBL23311454 | 0.73 | DHODH (0.39) | ALDH1A1GAAL3MBTL1LMNACTSS | |
| SCHEMBL27399412 | 0.71 | METAP1 (0.39) | — | |
| SCHEMBL3836742 | 0.70 | TTK (0.39) | KCNQ4KCNQ5CTSSCTSK | |
| SCHEMBL27078324 | 0.70 | CYP17A1 (0.38) | CTSSCTSKRAB9A | |
| SCHEMBL1066439 | 0.69 | METAP1 (0.45) | LMNAPI4KB | |
| SCHEMBL13136708 | 0.68 | SMN1; SMN2 (0.43) | ALDH1A1GAAL3MBTL1ABCB1LMNA | |
| SCHEMBL25408853 | 0.67 | AR (0.35) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129956-A1 | THIENOAZEPINE IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024129956-A1 | THIENOAZEPINE IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |