Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.35 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27078324 | 0.89 | CYP17A1 (0.38) | CYP17A1NAMPTRAB9AGPR119 | |
| SCHEMBL27399415 | 0.83 | ALDH1A1 (0.37) | ALDH1A1GAAL3MBTL1KCNQ4KCNQ5 | |
| SCHEMBL24255781 | 0.78 | AR (0.33) | ALDH1A1GAAL3MBTL1KCNQ4KCNQ5 | |
| SCHEMBL4725743 | 0.75 | NAMPT (0.43) | CYP17A1NAMPTRAB9A | |
| SCHEMBL23289646 | 0.74 | LMNA (0.37) | ALDH1A1GAAL3MBTL1KCNQ4KCNQ5 | |
| SCHEMBL6491640 | 0.74 | CYP17A1 (0.42) | CYP17A1KCNQ4KCNQ5NAMPTRAB9A | |
| SCHEMBL30132796 | 0.74 | CYP17A1 (0.42) | CYP17A1KCNQ4KCNQ5NAMPTRAB9A | |
| SCHEMBL14291975 | 0.74 | CYP17A1 (0.42) | CYP17A1NAMPTRAB9A | |
| SCHEMBL29957148 | 0.73 | CYP17A1 (0.47) | CYP17A1NAMPTRAB9A | |
| SCHEMBL1020140 | 0.73 | CYP17A1 (0.47) | CYP17A1NAMPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940168-A | 2-Amino-4-carboxamide-benzazepine immunoconjugates and uses thereof | 博尔特生物治疗药物有限公司 | 2024-04-26 | — | — | CN | disclosed |