Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.33 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.33 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25408853 | 0.88 | AR (0.35) | ARGSK3BDYRK1AMAPK14TTK | |
| SCHEMBL27399415 | 0.79 | ALDH1A1 (0.37) | KCNQ4KCNQ5ALDH1A1GAAL3MBTL1 | |
| SCHEMBL29260330 | 0.78 | CYP17A1 (0.35) | KCNQ4KCNQ5ALDH1A1GAAL3MBTL1 | |
| SCHEMBL23289646 | 0.77 | LMNA (0.37) | KCNQ4KCNQ5ALDH1A1GAAL3MBTL1 | |
| SCHEMBL6133253 | 0.73 | MAPK14 (0.40) | RAB9ALMNAGSK3BDYRK1AMAPK14 | |
| SCHEMBL26291956 | 0.72 | DRD2 (0.34) | ALDH1A1MAPTNPSR1LMNAMEN1 | |
| SCHEMBL23311454 | 0.70 | DHODH (0.39) | ALDH1A1GAAL3MBTL1MAPTNPC1 | |
| SCHEMBL6133365 | 0.69 | BRD9 (0.35) | ALDH1A1GAALMNAGSK3BDYRK1A | |
| SCHEMBL6133366 | 0.69 | BRD9 (0.35) | ALDH1A1GAALMNAGSK3BDYRK1A | |
| SCHEMBL26291990 | 0.69 | NAMPT (0.35) | ALDH1A1GAAL3MBTL1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230263903-A1 | PYRAZOLOAZEPINE IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2023-08-24 | — | — | US | disclosed |
| CN-116234586-A | Pyrazoloazepine immunoconjugates and uses thereof | 博尔特生物治疗药物有限公司 | 2023-06-06 | — | — | CN | disclosed |
| WO-2022036101-A1 | PYRAZOLOAZEPINE IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230263903-A1 | PYRAZOLOAZEPINE IMMUNOCONJUGATES, AND USES THEREOF | KCNJ5, IL5, CYP3A5 | AR 2796/4885KCNQ4 133/4885KCNQ5 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.