Sarcosine

Sarcosine

SCHEMBL27399476

CNCC(=O)O.O=C(O)C(=O)O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1SLC6A4

The experimentally established mechanism targets of Sarcosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTH P32929 1/20 0.40
LDHA P00338 1/20 0.39
SRR Q9GZT4 1/20 0.39
EGLN1 Q9GZT9 4/20 0.39
APEX1 P27695 1/20 0.38
ALDH1A1 P00352 2/20 0.37
LMNA P02545 2/20 0.37
MAPT P10636 1/20 0.37
PTGS2 P35354 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
FFAR3 O14843 2/20 0.37
KDM4E B2RXH2 1/20 0.35
KDM5C P41229 1/20 0.35
PHF8 Q9UPP1 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35
ALOX15 P16050 1/20 0.33
ECE1 P42892 1/20 0.32
CYP2D6 P10635 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HDAC3 O15379 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sarcosine SCHEMBL27886454 0.97 CTH (0.39) CTHLDHASRREGLN1APEX1
Sarcosine SCHEMBL29153526 0.97 CTH (0.39) CTHLDHASRREGLN1APEX1
Sarcosine SCHEMBL149 0.94
Sarcosine SCHEMBL26641423 0.94 LDHA (0.44) CTHLDHASRREGLN1APEX1
Sarcosine SCHEMBL31427574 0.94
Sarcosine SCHEMBL28259932 0.94
Sarcosine SCHEMBL156329 0.94 LDHA (0.44) CTHLDHASRREGLN1APEX1
Sarcosine SCHEMBL27882386 0.92 ACHE (0.37) CTHLDHASRREGLN1APEX1
Sarcosine SCHEMBL25435381 0.90
Sarcosine SCHEMBL3761484 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 583 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110312785-A Method for producing solid methylglycinediacetic acid (MGDA) alkali metal salt and solid particles 巴斯夫欧洲公司 2019-10-08 CN claimed
CN-109072135-A Mixtures of chelating agents and methods for preparing such mixtures 巴斯夫欧洲公司 2018-12-21 CN claimed
CN-108368460-A Aqueous solution containing high concentration of complexing agent 巴斯夫欧洲公司 2018-08-03 CN claimed
CN-106715668-A Detergent composition 巴斯夫欧洲公司 2017-05-24 CN claimed
CN-102159691-B Aqueous cutting fluid for use with diamond wire saw DOW GLOBAL TECHNOLOGIES LLC 2013-11-06 CN claimed
CN-103210075-A Automatic dishwashing composition INNOSPEC LTD 2013-07-17 CN claimed
CN-101300332-B Detergent composition RECKITT BENCKISER NV 2013-01-23 CN claimed
CN-101809139-B Detergent composition RECKITT BENCKISER NV 2012-08-29 CN claimed
CN-102498198-A Treatment of non-trans fats, fatty acids and sunscreen stains with chelating agents ECOLAB USA INC 2012-06-13 CN claimed
CN-102482659-A Detergent composition RECKITT BENCKISER NV 2012-05-30 CN claimed
CN-1253627-C Single-bath preparation of cellulosic materials NOVOZYMES NORTH AMERICA INC (US) 2006-04-26 CN claimed
CN-1723272-A Preparation of cellulosic material NOVOZYMES NORTH AMERICA INC (US) 2006-01-18 CN claimed
CN-1203760-C Bactericidal and fungicidal liquid preparations for industrial products AIR LIQUIDE SANTE INT (FR) 2005-06-01 CN claimed
CN-1564705-A Process for desulphurizing sour gases using catalysts containing aminocarboxylate groups which are inactive by oxidation BASF AG (DE) 2005-01-12 CN claimed
CN-1522323-A Single-bath preparation of cellulosic materials 诺维信北美公司 2004-08-18 CN claimed
CN-1407855-A Bactericidal and fungicidal liquid preparations for industrial products AIR LIQUIDE SANTE INT (FR) 2003-04-02 CN claimed
CN-1071998-C Use of combination of surfactants, chelating agents and essential oils for effective disinfection PROCTER & GAMBLE (US) 2001-10-03 CN claimed
CN-1295610-A Acidic cleaning compositions containing acidic proteases NOVO NORDISK AS (DK) 2001-05-16 CN claimed
CN-1229335-A Use of a mixture of surfactants, chelating agents and essential oils for effective disinfection PROCTER & GAMBLE (US) 1999-09-22 CN claimed
CN-1176656-A Laundry pretreatment with peroxide bleaches containing chelators for iron, copper or manganese for reduced fabric damage PROCTER & GAMBLE (US) 1998-03-18 CN claimed