Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HAT1 | O14929 | 2/20 | 0.49 |
| ▸ | EP300 | Q09472 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27395314 | 0.99 | LMNA (0.53) | LMNAHAT1EP300POLBALDH1A1 | |
| SCHEMBL15902165 | 0.74 | POLB (0.57) | LMNAHAT1EP300POLBALDH1A1 | |
| SCHEMBL5539343 | 0.74 | POLB (0.57) | LMNAHAT1EP300POLBALDH1A1 | |
| SCHEMBL27396427 | 0.74 | POLB (0.57) | LMNAHAT1EP300POLBALDH1A1 | |
| SCHEMBL4759834 | 0.74 | LMNA (0.60) | LMNAPOLBALDH1A1MITFMAPT | |
| SCHEMBL4192667 | 0.73 | EPHX1 (0.49) | ALDH1A1KMT2A | |
| SCHEMBL27601267 | 0.73 | EPHX1 (0.49) | ALDH1A1KMT2A | |
| SCHEMBL27601264 | 0.73 | NR4A2 (0.53) | LMNAPOLBALDH1A1KMT2ATSHR | |
| SCHEMBL27552132 | 0.73 | LMNA (0.56) | LMNAHAT1EP300POLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL4208521 | 0.72 | EPHX1 (0.47) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1081676-A | The indoles and the indazole derivatives that are used for the treatment and the prevention of cerebral disorders, their preparation and application | SANKYO CO (JP) | 1994-02-09 | — | — | CN | disclosed |