Sugi Predict

Sugi Predict / Compounds / SCHEMBL5539343

SCHEMBL5539343

SCHEMBL5539343

Cn1cc(C(=O)C(Cl)c2ccccc2)c2ccccc21

nearest known ligand 0.72

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.57
▸ LMNA P02545 2/20 0.56
▸ ALDH1A1 P00352 2/20 0.56
▸ KMT2A Q03164 2/20 0.56
▸ MITF O75030 1/20 0.56
▸ MAPT P10636 1/20 0.56
▸ NPSR1 Q6W5P4 1/20 0.56
▸ NR4A2 P43354 1/20 0.54
▸ HTT P42858 1/20 0.52
▸ SMN1; SMN2 Q16637 1/20 0.51
▸ MEN1 O00255 1/20 0.50
▸ HAT1 O14929 2/20 0.48
▸ EP300 Q09472 2/20 0.48
▸ KDM4E B2RXH2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15901852 0.85 ALDH1A1 (0.45) POLBLMNAALDH1A1KMT2AMITF
SCHEMBL15902165 0.82 POLB (0.57) POLBLMNAALDH1A1KMT2AMITF
SCHEMBL27396427 0.82 POLB (0.57) POLBLMNAALDH1A1KMT2AMITF
SCHEMBL15901743 0.81 HAT1 (0.59) ALDH1A1KMT2AMAPTSMN1; SMN2MEN1
SCHEMBL17321400 0.80 ALDH1A1 (0.61) POLBLMNAALDH1A1KMT2AMITF
SCHEMBL15902394 0.79 CNR2 (0.59) LMNAALDH1A1MAPTNPSR1SMN1; SMN2
SCHEMBL15902256 0.79 LMNA (0.46) LMNAALDH1A1KMT2ASMN1; SMN2MEN1
SCHEMBL14832853 0.79 CNR2 (0.56) ALDH1A1KMT2ASMN1; SMN2MEN1HAT1
SCHEMBL29164608 0.78 HTT (0.62) POLBLMNAALDH1A1KMT2AMITF
SCHEMBL29965768 0.77 POLB (0.72) POLBLMNAALDH1A1KMT2AMITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12012411-B2 Viral replication inhibitors KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2024-06-18 — — US disclosed
US-20220106321-A1 VIRAL REPLICATION INHIBITORS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2022-04-07 — — US disclosed
US-11279704-B2 Viral replication inhibitors KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2022-03-22 — — US disclosed
CN-108440370-B Inhibitors of viral replication 鲁汶天主教大学 2021-07-30 — — CN disclosed
EP-3617192-A1 VIRAL REPLICATION INHIBITORS Katholieke Universiteit Leuven K.U. Leuven R&D (BE) 2020-03-04 — — EP disclosed
US-10550123-B2 Viral replication inhibitors KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) 2020-02-04 — — US disclosed
US-20190337954-A1 VIRAL REPLICATION INHIBITORS KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) 2019-11-07 — — US disclosed
EP-2760831-B1 VIRAL REPLICATION INHIBITORS UNIV LEUVEN KATH (BE) 2019-08-07 — — EP disclosed
EP-2760831-A1 VIRAL REPLICATION INHIBITORS Katholieke Universiteit Leuven (BE) 2014-08-06 — — EP disclosed
US-20140213586-A1 VIRAL REPLICATION INHIBITORS KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) 2014-07-31 — — US disclosed
US-20020058280-A1 Metal chelate containing compositions for use in chemiluminescent assays SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) 2002-05-16 — — US disclosed
US-6340599-B1 TERBIUM, DYSPROSIUM, SAMARIUM, OSMIUM, OR RUTHENIUM COMPLEX WITH UNSATURATED OXYARYL COMPOUND DADE BEHRING MARBURG GMBH (DE) 2002-01-22 — — US disclosed
EP-1091211-A1 Metal chelate containing compositions for use in chemiluminescent assays Dade Behring Marburg GmbH (DE) 2001-04-11 — — EP disclosed
US-6180354-B1 RARE EARTH COMPLEX DADE BEHRING MARBURG GMBH (DE) 2001-01-30 — — US disclosed
US-5811311-A CONTAINING LATEX WITH SPECIFIC BINDING PAIR INCORPORATED THEREIN DADE BEHRING MARBURG GMBH (DE) 1998-09-22 — — US disclosed
US-5780646-A CHEMILUMINESCENT COMPOUNDS FOR MEDICAL DIAGNOSIS BEHRINGWERKE AG (DE) 1998-07-14 — — US disclosed
US-5578498-A FOR DETERMINING AN ANALYTE IN A SAMPLE BEHRINGWERKE AG (DE) 1996-11-26 — — US disclosed
EP-0730738-A1 METAL CHELATE CONTAINING COMPOSITIONS FOR USE IN CHEMILUMINESCENT ASSAYS BEHRINGWERKE AG (DE) 1996-09-11 — — EP disclosed
US-5536834-A CHEMILUMINESCENCE COMPOUNDS FOR MEDICAL DIAGNOSIS BEHRINGWERKE AG (DE) 1996-07-16 — — US disclosed
WO-1995014928-A1 METAL CHELATE CONTAINING COMPOSITIONS FOR USE IN CHEMILUMINESCENT ASSAYS BEHRINGWERKE AG (DE) 1995-06-01 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140213586-A1 VIRAL REPLICATION INHIBITORS EIF2AK2, MAVS, ZC3HAV1 POLB 81/4885LMNA 2214/4885ALDH1A1 4277/4885
US-11279704-B2 Viral replication inhibitors EIF2AK2, MAVS, ZC3HAV1 POLB 81/4885LMNA 2214/4885ALDH1A1 4277/4885
US-20190337954-A1 VIRAL REPLICATION INHIBITORS EIF2AK2, MAVS, ZC3HAV1 POLB 81/4885LMNA 2214/4885ALDH1A1 4277/4885
US-10550123-B2 Viral replication inhibitors EIF2AK2, MAVS, ZC3HAV1 POLB 81/4885LMNA 2214/4885ALDH1A1 4277/4885
US-20220106321-A1 VIRAL REPLICATION INHIBITORS EIF2AK2, MAVS, ZC3HAV1 POLB 81/4885LMNA 2214/4885ALDH1A1 4277/4885
US-12012411-B2 Viral replication inhibitors EIF2AK2, MAVS, ZC3HAV1 POLB 81/4885LMNA 2214/4885ALDH1A1 4277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.