Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 18/20 | 0.40 |
| ▸ | DRD4 | P21917 | 18/20 | 0.40 |
| ▸ | DRD3 | P35462 | 18/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27444255 | 0.88 | DRD2 (0.40) | DRD2DRD4DRD3 | |
| SCHEMBL27405699 | 0.87 | OPRM1 (0.43) | DRD3 | |
| SCHEMBL27469099 | 0.86 | CYP19A1 (0.38) | — | |
| SCHEMBL27401367 | 0.86 | OPRM1 (0.37) | — | |
| SCHEMBL27403252 | 0.80 | SLC6A2 (0.38) | — | |
| SCHEMBL28780773 | 0.79 | IDH1 (0.34) | — | |
| SCHEMBL27406358 | 0.76 | MEN1 (0.34) | — | |
| SCHEMBL6995994 | 0.71 | GAA (0.41) | — | |
| SCHEMBL27896893 | 0.67 | DRD3 (0.38) | DRD2DRD4DRD3 | |
| SCHEMBL3554785 | 0.67 | DRD3 (0.54) | DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1098264-C | Substituted 4- (1H-benzimidazol-2-yl-amino) piperidines for the treatment of allergic diseases | AVENTIS PHARMA INC (US) | 2003-01-08 | — | — | CN | disclosed |
| CN-1080262-C | Novel substituted 4-(1H-benzimidazol-2-YL) [1,4] diazepanes useful for the treatment of allergic diseases | HOECHST MARION ROUSSEL INC (US) | 2002-03-06 | — | — | CN | disclosed |
| CN-1207097-A | Novel substituted 4- (1H-benzimidazol-2-yl) [1,4] diazepanes useful for the treatment of allergic diseases | HOECHST MARION ROUSSEL INC (US) | 1999-02-03 | — | — | CN | disclosed |
| CN-1202894-A | Substituted 4-(1H-benzimidzol-2-yl-amino) piepridines useful for the treatment of allergic diseases | HOECHST MARION ROUSSEL INC (US) | 1998-12-23 | — | — | CN | disclosed |