Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 11/20 | 0.38 |
| ▸ | DRD2 | P14416 | 10/20 | 0.38 |
| ▸ | DRD4 | P21917 | 10/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11553511 | 0.78 | DRD2 (0.38) | DRD3DRD2DRD4HDAC1 | |
| SCHEMBL4697560 | 0.76 | CA1 (0.38) | OPRM1OPRL1OPRD1OPRK1HDAC1 | |
| SCHEMBL25475291 | 0.76 | MME (0.38) | DRD3DRD2DRD4OPRM1 | |
| SCHEMBL2720401 | 0.75 | CA1 (0.37) | HPGDHDAC1 | |
| SCHEMBL24944598 | 0.75 | OPRM1 (0.51) | DRD3OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL16908880 | 0.74 | FPR2 (0.40) | OPRM1OPRD1HPGDHDAC1 | |
| SCHEMBL27970983 | 0.72 | ALDH1A1 (0.39) | DRD3DRD2DRD4OPRM1OPRD1 | |
| SCHEMBL17674529 | 0.72 | KMT2A (0.45) | HDAC1 | |
| SCHEMBL25475391 | 0.72 | MME (0.39) | DRD2OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL29704406 | 0.72 | DRD3 (0.58) | DRD3DRD2DRD4OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102770415-A | Polycyclic compounds as lysophosphatidic acid receptor antagonists | AMIRA PHARMACEUTICALS INC | 2012-11-07 | — | — | CN | disclosed |