Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 19/20 | 0.58 |
| ▸ | FLT3 | P36888 | 19/20 | 0.58 |
| ▸ | KIT | P10721 | 5/20 | 0.58 |
| ▸ | AURKA | O14965 | 1/20 | 0.58 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.58 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.58 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.58 |
| ▸ | CDK2 | P24941 | 1/20 | 0.58 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.58 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.58 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.58 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.58 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.58 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.58 |
| ▸ | ULK1 | O75385 | 1/20 | 0.54 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27087847 | 0.98 | CHEK1 (0.62) | CHEK1FLT3KITAURKARPS6KA5 | |
| SCHEMBL27403132 | 0.98 | CHEK1 (0.58) | CHEK1FLT3KITAURKARPS6KA5 | |
| SCHEMBL29989342 | 0.98 | CHEK1 (0.62) | CHEK1FLT3KITAURKARPS6KA5 | |
| SCHEMBL30800585 | 0.95 | CHEK1 (0.61) | CHEK1FLT3KITAURKARPS6KA5 | |
| SCHEMBL27087791 | 0.95 | CHEK1 (0.61) | CHEK1FLT3KITAURKARPS6KA5 | |
| SCHEMBL27402885 | 0.89 | CHEK1 (0.56) | CHEK1FLT3KITAURKARPS6KA5 | |
| SCHEMBL1917257 | 0.89 | CHEK1 (0.56) | CHEK1FLT3KITAURKARPS6KA5 | |
| SCHEMBL30800579 | 0.87 | CHEK1 (0.53) | CHEK1FLT3KITAURKARPS6KA5 | |
| SCHEMBL27402977 | 0.87 | CHEK1 (0.53) | CHEK1FLT3KITAURKARPS6KA5 | |
| SCHEMBL29989296 | 0.86 | CHEK1 (0.63) | CHEK1FLT3KITAURKARPS6KA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208934-A1 | ULK1/2 INHIBITORS AND THEIR USE THEREOF | LIFEARC (GB) | 2024-06-27 | — | — | US | disclosed |
| US-20240208934-A1 | ULK1/2 INHIBITORS AND THEIR USE THEREOF | LIFEARC (GB) | 2024-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208934-A1 | ULK1/2 INHIBITORS AND THEIR USE THEREOF | ULK1, ULK2, ULK3 | CHEK1 10/4885FLT3 919/4885KIT 3185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.