Chlorobenzene

Chlorobenzene

SCHEMBL27403290

Clc1ccccc1.N.NC(=O)N=S(=O)=O

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
L3MBTL1 Q9Y468 5/20 0.39
MAPT P10636 3/20 0.39
PARP1 P09874 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 2/20 0.37
POLB P06746 1/20 0.37
CYP3A4 P08684 1/20 0.37
RECQL P46063 1/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
GRIN2B Q13224 1/20 0.36
HTT P42858 1/20 0.36
ALOX15 P16050 1/20 0.35
SCN5A Q14524 1/20 0.35
SCN2A Q99250 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorobenzene SCHEMBL21594815 0.98 TSHR (0.46) TSHRCES2CES1L3MBTL1MAPT
Benzene SCHEMBL3120365 0.80 CYP3A4 (0.37) TSHRL3MBTL1MAPTPARP1CYP1A2
Aniline SCHEMBL27368335 0.79 TSHR (0.48) TSHRL3MBTL1MAPTPARP1CYP1A2
Naphthalene SCHEMBL27608457 0.79 CYP2A6 (0.38) TSHRCES2CES1L3MBTL1MAPT
Chlorobenzene SCHEMBL27488158 0.78 TSHR (0.65) TSHRCES2CES1L3MBTL1MAPT
Chlorobenzene SCHEMBL9576941 0.78 TSHR (0.65) TSHRCES2CES1L3MBTL1MAPT
Benzene SCHEMBL27536972 0.78 CYP3A4 (0.35) TSHRL3MBTL1MAPTPARP1CYP1A2
Benzene SCHEMBL28203037 0.78 CYP3A4 (0.35) TSHRL3MBTL1MAPTPARP1CYP1A2
Toluene SCHEMBL8599249 0.78 LMNA (0.46) TSHRCES2CES1L3MBTL1MAPT
Chlorobenzene SCHEMBL27687167 0.77 TSHR (0.50) TSHRCES2CES1L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1077838-A The sweep-out method of spray tank DU PONT (US) 1993-11-03 CN disclosed