Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27398776 | 0.87 | SLC18A3 (0.35) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23085113 | 0.87 | SLC18A3 (0.35) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27398613 | 0.85 | MEN1 (0.42) | MEN1KMT2APPARDMAPK1HRH4 | |
| SCHEMBL27398768 | 0.82 | KMT2A (0.43) | MEN1KMT2APPARDMAPK1HRH4 | |
| SCHEMBL25703473 | 0.82 | LTA4H (0.33) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL26483486 | 0.77 | KMT2A (0.46) | MEN1KMT2AMAPK1 | |
| SCHEMBL25703442 | 0.77 | ATM (0.34) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25703421 | 0.76 | SIGMAR1 (0.37) | SLC6A2SLC6A4SLC6A3SMN1; SMN2 | |
| SCHEMBL22593577 | 0.75 | MEN1 (0.43) | MEN1KMT2APPARDMAPK1SMN1; SMN2 | |
| SCHEMBL6589364 | 0.74 | MEN1 (0.43) | MEN1KMT2APPARDMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129479-A2 | CYCLIC PEPTIDES AS PET IMAGING AGENTS OF GRANZYME B | MERCK SHARP & DOHME LLC (US) | 2024-06-20 | — | — | WO | disclosed |