Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23085113 | 1.00 | SLC18A3 (0.35) | SLC18A3SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25703473 | 0.92 | LTA4H (0.33) | SLC18A3SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25703442 | 0.89 | ATM (0.34) | SLC18A3SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25703421 | 0.89 | SIGMAR1 (0.37) | SLC18A3SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27403757 | 0.87 | MEN1 (0.40) | SLC6A2SLC6A4SLC6A3SMN1; SMN2MEN1 | |
| SCHEMBL22593578 | 0.86 | CA2 (0.41) | SLC18A3SIGMAR1APEX1BLMPMP22 | |
| SCHEMBL22815239 | 0.85 | SLC18A3 (0.38) | SLC18A3SIGMAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL27398620 | 0.85 | SLC18A3 (0.38) | SLC18A3SIGMAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL30329419 | 0.83 | CA2 (0.40) | SLC18A3SIGMAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL25162267 | 0.82 | SLC18A3 (0.35) | SLC18A3SIGMAR1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129479-A2 | CYCLIC PEPTIDES AS PET IMAGING AGENTS OF GRANZYME B | MERCK SHARP & DOHME LLC (US) | 2024-06-20 | — | — | WO | disclosed |