Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CCL2 | P13500 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9782939 | 0.86 | THRA (0.46) | MAPK1CA12CA1CA2CA7 | |
| SCHEMBL7850478 | 0.84 | CYP3A4 (0.42) | MAPK1CA12CA1CA2CA7 | |
| SCHEMBL10983336 | 0.81 | NQO1 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8019643 | 0.81 | THRA (0.52) | — | |
| SCHEMBL8251636 | 0.80 | L3MBTL1 (0.45) | MAPK1INPPL1CA12CA1CA2 | |
| SCHEMBL13624065 | 0.79 | MAPK1 (0.41) | MAPK1INPPL1CA12CA1CA2 | |
| SCHEMBL14239879 | 0.79 | ALDH1A1 (0.61) | MAPK1INPPL1CA12CA1CA2 | |
| SCHEMBL22638161 | 0.79 | MAPK1 (0.44) | MAPK1INPPL1CA12CA1CA2 | |
| SCHEMBL126703 | 0.78 | CA12 (0.62) | MAPK1CA12CA1CA2CA7 | |
| SCHEMBL6706305 | 0.78 | FFAR1 (0.48) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1106663-A | Thienopyrimidine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-08-16 | — | — | CN | disclosed |