Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14509190 | 0.83 | KDM4E (0.34) | ITGB3ITGA2BKDM4EMAPK1HIF1A | |
| SCHEMBL25477138 | 0.83 | KDM4E (0.34) | ITGB3ITGA2BKDM4EMAPK1HIF1A | |
| SCHEMBL14509061 | 0.79 | KISS1R (0.38) | KDM4EMAPK1HIF1APAOX | |
| SCHEMBL18233190 | 0.79 | KISS1R (0.38) | KDM4EMAPK1HIF1APAOX | |
| SCHEMBL18233928 | 0.78 | BLM (0.46) | ITGB3ITGA2BKDM4EMAPK1HIF1A | |
| SCHEMBL15030995 | 0.78 | BLM (0.46) | ITGB3ITGA2BKDM4EMAPK1HIF1A | |
| SCHEMBL22807623 | 0.76 | CNR1 (0.33) | ITGB3ITGA2B | |
| SCHEMBL19538524 | 0.76 | — | — | |
| SCHEMBL14402902 | 0.75 | KISS1R (0.39) | KDM4EMAPK1HIF1A | |
| SCHEMBL16627562 | 0.74 | KDM4E (0.40) | ITGB3ITGA2BKDM4EMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024108198-A2 | METHODS OF TREATING OBESITY WITH AN MC4R AGONIST | RHYTHM PHARMACEUTICALS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |