SCHEMBL14402902

SCHEMBL14402902

CNC(=O)[C@@H](C)CCCNC(C)=N

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ HIF1A Q16665 1/20 0.33
▸ DPP7 Q9UHL4 2/20 0.32
▸ CACNA1B Q00975 2/20 0.31
▸ CNR1 P21554 1/20 0.31
▸ ALDH1A2 O94788 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ ALDH2 P05091 1/20 0.31
▸ ALDH1A3 P47895 1/20 0.31
▸ MEN1 O00255 1/20 0.30
▸ GAA P10253 1/20 0.30
▸ KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27354286 0.84 ALOX15 (0.37) KISS1RDPP7MEN1KMT2A
SCHEMBL18233190 0.83 KISS1R (0.38) KISS1RKDM4EMAPK1HIF1ADPP7
SCHEMBL14509061 0.83 KISS1R (0.38) KISS1RKDM4EMAPK1HIF1ADPP7
SCHEMBL18233928 0.81 BLM (0.46) KISS1RKDM4EMAPK1HIF1AMEN1
SCHEMBL15030995 0.81 BLM (0.46) KISS1RKDM4EMAPK1HIF1AMEN1
SCHEMBL14769718 0.81 DPP7 (0.49) KISS1RDPP7
SCHEMBL13319577 0.81 DPP7 (0.49) KISS1RDPP7
SCHEMBL22807623 0.80 CNR1 (0.33) KISS1RDPP7CNR1
SCHEMBL25477138 0.80 KDM4E (0.34) KISS1RKDM4EMAPK1HIF1ADPP7
SCHEMBL14509190 0.80 KDM4E (0.34) KISS1RKDM4EMAPK1HIF1ADPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8759104-B2 Cationic lipids THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2014-06-24 — — US disclosed
US-20130065308-A1 CATIONIC LIPIDS THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2013-03-14 — — US disclosed
WO-2007115182-A2 LINEAR NATRIURETIC PEPTIDE CONSTRUCTS PALATIN TECHNOLOGIES, INC. (US) 2007-10-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130065308-A1 CATIONIC LIPIDS PLIN5, LPCAT3, IPO5 KISS1R 2809/4885KDM4E 2442/4885MAPK1 4293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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