Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPY4R | P50391 | 2/20 | 0.30 |
| ▸ | RRM1 | P23921 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | NPY1R | P25929 | 1/20 | 0.30 |
| ▸ | NPY2R | P49146 | 1/20 | 0.30 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25477138 | 1.00 | KDM4E (0.34) | KDM4EMAPK1HIF1AITGB3ITGA2B | |
| SCHEMBL13402408 | 0.87 | ALOX15 (0.40) | ITGB3ITGA2BDPP7MEN1KMT2A | |
| SCHEMBL8297085 | 0.87 | ALOX15 (0.40) | ITGB3ITGA2BDPP7MEN1KMT2A | |
| SCHEMBL17793248 | 0.87 | ALOX15 (0.40) | ITGB3ITGA2BDPP7MEN1KMT2A | |
| SCHEMBL14509061 | 0.85 | KISS1R (0.38) | KDM4EMAPK1HIF1APAOXDPP7 | |
| SCHEMBL18233190 | 0.85 | KISS1R (0.38) | KDM4EMAPK1HIF1APAOXDPP7 | |
| SCHEMBL23106058 | 0.85 | KDM4E (0.52) | KDM4EMAPK1HIF1APAOXDPP7 | |
| SCHEMBL15030995 | 0.83 | BLM (0.46) | KDM4EMAPK1HIF1AITGB3ITGA2B | |
| SCHEMBL18233928 | 0.83 | BLM (0.46) | KDM4EMAPK1HIF1AITGB3ITGA2B | |
| SCHEMBL27405296 | 0.83 | ITGB3 (0.31) | KDM4EMAPK1HIF1AITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105783-A1 | Process for the manufacture of peptide facilitators of reverse cholesterol transport | SIRCAR JAGADISH C | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105783-A1 | Process for the manufacture of peptide facilitators of reverse cholesterol transport | CETP, NPC1L1, SLC10A1 | KDM4E 4154/4885MAPK1 1802/4885HIF1A 583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.