Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27405399 | 1.00 | MIF (0.46) | MIFCTSSCTSKTRPA1PPARG | |
| SCHEMBL18660861 | 0.88 | PPARG (0.49) | TRPA1PPARGPPARACA1CA2 | |
| SCHEMBL18660862 | 0.88 | PPARG (0.49) | TRPA1PPARGPPARACA1CA2 | |
| SCHEMBL2791437 | 0.86 | ALDH1A1 (0.49) | CTSSCTSKTRPA1KDM4EGLA | |
| SCHEMBL21180491 | 0.86 | TRPA1 (0.48) | CTSSCTSKTRPA1PPARGPPARA | |
| SCHEMBL24298843 | 0.86 | HDAC1 (0.45) | TRPA1PPARGPPARAKDM4EGLA | |
| SCHEMBL2762834 | 0.86 | TRPA1 (0.52) | TRPA1PPARGPPARAKDM4EGLA | |
| SCHEMBL18660710 | 0.86 | ALDH1A1 (0.49) | CTSSCTSKTRPA1KDM4EGLA | |
| SCHEMBL24298844 | 0.86 | HDAC1 (0.45) | TRPA1PPARGPPARAKDM4EGLA | |
| SCHEMBL3871050 | 0.86 | TRPA1 (0.48) | CTSSCTSKTRPA1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1075062-C | Acetic acid derivatives | HOFFMANN LA ROCHE (CH) | 2001-11-21 | — | — | CN | disclosed |