Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9880274 | 0.78 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL23075157 | 0.74 | SMN1; SMN2 (0.34) | EPHX1 | |
| SCHEMBL15335066 | 0.71 | CYP3A4 (0.35) | EPHX1CYP2C9TSHR | |
| SCHEMBL23084056 | 0.71 | EPHX1 (0.31) | EPHX1 | |
| SCHEMBL24606655 | 0.70 | MAPT (0.38) | — | |
| SCHEMBL23075810 | 0.69 | FAAH (0.35) | EPHX1 | |
| SCHEMBL25298727 | 0.69 | USP2 (0.33) | EPHX1CYP2C9TSHR | |
| SCHEMBL27405684 | 0.68 | CYP2D6 (0.46) | CYP2C9TSHR | |
| SCHEMBL13004338 | 0.68 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL13060360 | 0.68 | VNN1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208941-A1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS | TYRA BIOSCIENCES, INC. | 2024-06-27 | — | — | US | disclosed |
| US-20240208941-A1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS | TYRA BIOSCIENCES, INC. | 2024-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208941-A1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS | FGFR1, FGFR2, FGFR3 | EPHX1 2625/4885CYP2C9 2177/4885TSHR 2777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.