Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | KLK7 | P49862 | 2/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.46 |
| ▸ | YAP1 | P46937 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 3/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31646670 | 0.91 | KLK7 (0.50) | ITGB3ITGA2BPDE4BKLK7KLK5 | |
| SCHEMBL28610469 | 0.89 | HTT (0.52) | ITGB3ITGA2BPDE4BKLK7KLK5 | |
| SCHEMBL27406338 | 0.83 | PDE4B (0.43) | PDE4BCTSLHTTCTSKCTSS | |
| SCHEMBL28743990 | 0.83 | YAP1 (0.49) | PRMT5WDR77KLK7KLK5CTSL | |
| SCHEMBL20158205 | 0.83 | YAP1 (0.49) | PRMT5WDR77KLK7KLK5CTSL | |
| SCHEMBL31646594 | 0.83 | PPARA (0.48) | ITGB3ITGA2BPDE4BKLK7KLK5 | |
| SCHEMBL28610465 | 0.83 | PPARA (0.55) | ITGB3ITGA2BPRMT5WDR77KLK7 | |
| SCHEMBL28610466 | 0.83 | PPARA (0.55) | ITGB3ITGA2BPRMT5WDR77KLK7 | |
| SCHEMBL22433813 | 0.82 | YAP1 (0.56) | PRMT5WDR77CTSLYAP1HTT | |
| SCHEMBL12025747 | 0.82 | YAP1 (0.57) | ITGB3ITGA2BCTSLYAP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208968-A1 | ALPHA V BETA 6 AND ALPHA V BETA 1 INTEGRIN INHIBITORS AND USES THEREOF | DICE MOLECULES SV, INC. | 2024-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208968-A1 | ALPHA V BETA 6 AND ALPHA V BETA 1 INTEGRIN INHIBITORS AND USES THEREOF | ITGB1, ITGA1, ITGAV | ITGB3 10/4885ITGA2B 9/4885PDE4B 1596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.