Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | YAP1 | P46937 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KLK7 | P49862 | 2/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28610465 | 0.93 | PPARA (0.55) | HTTYAP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL28610466 | 0.93 | PPARA (0.55) | HTTYAP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL22433813 | 0.93 | YAP1 (0.56) | HTTYAP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31646670 | 0.90 | KLK7 (0.50) | HTTYAP1KLK7KLK5MAPK1 | |
| SCHEMBL27406331 | 0.89 | ITGB3 (0.51) | HTTYAP1KLK7KLK5MAPK1 | |
| SCHEMBL29968272 | 0.87 | YAP1 (0.57) | HTTYAP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12025774 | 0.87 | YAP1 (0.57) | HTTYAP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29189817 | 0.87 | YAP1 (0.57) | HTTYAP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12025747 | 0.87 | YAP1 (0.57) | HTTYAP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL24979440 | 0.86 | YAP1 (0.54) | HTTYAP1MAPK1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107098871-B | Phenyl propionamide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-07-02 | — | — | CN | disclosed |