Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27653530 | 0.75 | HTR1B (0.55) | HTR1BCHRM2CHRM1CHRM3TAAR1 | |
| SCHEMBL2099512 | 0.74 | CHRM2 (0.66) | HTR1BCHRM2CHRM1CHRM3TAAR1 | |
| SCHEMBL8383654 | 0.74 | NISCH (0.46) | — | |
| SCHEMBL28951257 | 0.70 | CHRM2 (0.56) | HTR1BCHRM2CHRM1CHRM3TAAR1 | |
| SCHEMBL31739258 | 0.69 | LTA4H (0.67) | HTR1BCHRM2CHRM1CHRM3TAAR1 | |
| SCHEMBL2092574 | 0.69 | LTA4H (0.67) | HTR1BCHRM2CHRM1CHRM3TAAR1 | |
| SCHEMBL14191204 | 0.68 | LTA4H (0.70) | HTR1BCHRM2CHRM1CHRM3TAAR1 | |
| SCHEMBL29370584 | 0.68 | CHRM2 (0.68) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL297410 | 0.68 | CHRM2 (0.68) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL1501195 | 0.67 | LMNA (0.58) | HTR1BCHRM2CHRM1CHRM3TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1067050-C | Insecticidal N'-substituted-N, N'-diacylhydrazines | ROHM & HAAS (US) | 2001-06-13 | — | — | CN | disclosed |