Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 6/20 | 0.39 |
| ▸ | ADH1C | P00326 | 4/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27391484 | 0.98 | ADH1A (0.35) | ADH1AADH1CFAAHPHGDHMGLL | |
| SCHEMBL27394443 | 0.79 | CYP1A2 (0.39) | ADH1AADH1CEPHX1 | |
| SCHEMBL1685454 | 0.78 | ADH1A (0.40) | ADH1AADH1CFAAHPHGDHMGLL | |
| SCHEMBL23838294 | 0.77 | PIK3CD (0.44) | — | |
| SCHEMBL11774321 | 0.77 | ADH1C (0.43) | ADH1AADH1CFAAHPHGDHMGLL | |
| SCHEMBL10863722 | 0.74 | ADH1A (0.42) | ADH1AADH1CPHGDHALDH1A1EPHX1 | |
| SCHEMBL18977692 | 0.73 | ADH1C (0.39) | ADH1AADH1CEPHX1ADH1B | |
| SCHEMBL11488025 | 0.73 | KDM4E (0.35) | ADH1AADH1CFAAHPHGDHMGLL | |
| SCHEMBL8979133 | 0.72 | ADH1A (0.42) | ADH1AADH1CFAAHPHGDHMGLL | |
| SCHEMBL11796297 | 0.71 | ADH1A (0.39) | ADH1AADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1063442-C | Aminothiazole derivatives, drug containing the same and intermediate in the production of the compounds | ZERIA PHARM CO LTD (JP) | 2001-03-21 | — | — | CN | disclosed |
| CN-1184471-A | Aminothiazole derivatives, drug containing the same and intermediate in the production of the compounds | ZERIA PHARM CO LTD (JP) | 1998-06-10 | — | — | CN | disclosed |