Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 4/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL200716 | 0.95 | PNMT (0.58) | PNMTADRA2ASIRT2MAPTALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28209706 | 0.93 | PNMT (0.57) | PNMTADRA2ASIRT2MAPTALDH1A1 | |
| Methane SCHEMBL27508397 | 0.93 | PNMT (0.57) | PNMTADRA2ASIRT2MAPTALDH1A1 | |
| SCHEMBL27599386 | 0.91 | CA12 (0.50) | PNMTADRA2ASIRT2MAPTALDH1A1 | |
| Butane SCHEMBL27459660 | 0.88 | PNMT (0.51) | PNMTADRA2ASIRT2MAPTALDH1A1 | |
| Acetaldehyde SCHEMBL27415337 | 0.88 | PNMT (0.51) | PNMTADRA2ASIRT2MAPTALDH1A1 | |
| Sulfuric Acid SCHEMBL29269875 | 0.88 | PNMT (0.51) | PNMTADRA2ASIRT2MAPTALDH1A1 | |
| Acetic Acid SCHEMBL28007453 | 0.86 | SIRT2 (0.52) | PNMTADRA2ASIRT2MAPTALDH1A1 | |
| SCHEMBL28171953 | 0.86 | SIRT2 (0.52) | PNMTADRA2ASIRT2MAPTALDH1A1 | |
| Pyrimidine SCHEMBL28303381 | 0.86 | ADRA2A (0.50) | PNMTADRA2ASIRT2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1086819-A | Novel compounds having 5-hydroxytryptamine receptor antagonistic activity | SMITHKLINE BEECHAM PLC (GB) | 1994-05-18 | — | — | CN | disclosed |