Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | ACLY | P53396 | 1/20 | 0.57 |
| ▸ | PNLIP | P16233 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | SMO | Q99835 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13171396 | 0.87 | PNLIP (0.64) | KMT2AMEN1NPC1RAB9APNLIP | |
| SCHEMBL27315886 | 0.83 | KMT2A (0.64) | KMT2AMEN1NPC1RAB9AACLY | |
| SCHEMBL27353059 | 0.83 | DHODH (0.63) | KMT2AMEN1ACLYPNLIPPPARG | |
| SCHEMBL19976062 | 0.82 | NPC1 (0.73) | KMT2AMEN1NPC1RAB9AACLY | |
| SCHEMBL9197072 | 0.82 | F2R (0.55) | KMT2AMEN1NPC1RAB9APNLIP | |
| SCHEMBL17538444 | 0.81 | CYP1A2 (0.62) | KMT2AMEN1ACLYPPARGPPARA | |
| SCHEMBL11592306 | 0.81 | SMO (0.65) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL7252190 | 0.81 | NPC1 (0.65) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL17154495 | 0.80 | GRM4 (0.63) | KMT2AMEN1NPC1RAB9APNLIP | |
| SCHEMBL10489740 | 0.79 | NPC1 (0.69) | KMT2AMEN1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051036-A | The treatment of HIV (human immunodeficiency virus) infections and in treatment used compound | UNIROYAL CHEM CO INC (US) | 1991-05-01 | — | — | CN | claimed |