Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.56 |
| ▸ | CA2 | P00918 | 5/20 | 0.56 |
| ▸ | CA12 | O43570 | 4/20 | 0.56 |
| ▸ | CA9 | Q16790 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13128982 | 0.92 | CA1 (0.48) | CA1CA2CA12CA9MEN1 | |
| SCHEMBL13128925 | 0.80 | HPGD (0.51) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL14161620 | 0.77 | POLB (0.60) | CA1CA2CA12CA9MEN1 | |
| SCHEMBL9833561 | 0.77 | CA1 (0.62) | CA1CA2CA12CA9MEN1 | |
| SCHEMBL14160305 | 0.75 | PTK2B (0.52) | MEN1KMT2AMAPTPOLBLMNA | |
| SCHEMBL7753274 | 0.73 | SMN1; SMN2 (0.55) | CA1CA2CA12CA9MEN1 | |
| SCHEMBL9832525 | 0.72 | MEN1 (0.62) | CA1CA2CA12CA9MEN1 | |
| SCHEMBL31675011 | 0.72 | CA12 (0.60) | CA1CA2CA12CA9MEN1 | |
| SCHEMBL15647634 | 0.72 | MAPT (0.60) | MEN1KMT2AMAPTPOLBLMNA | |
| SCHEMBL2740968 | 0.72 | MAPT (0.66) | MEN1KMT2AMAPTPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088772-B2 | Sulfonamides and their use as a medicament | THE GENETICS COMPANY, INC. (CH) | 2012-01-03 | — | — | US | disclosed |
| US-8088772-B2 | Sulfonamides and their use as a medicament | THE GENETICS COMPANY, INC. (CH) | 2012-01-03 | — | — | US | disclosed |