Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2B | Q14289 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13128920 | 0.86 | PTK2B (0.63) | PTK2BSMN1; SMN2KDM4ETSHRL3MBTL1 | |
| SCHEMBL2740945 | 0.85 | CRHBP (0.51) | PTK2BSMN1; SMN2KDM4ETSHRL3MBTL1 | |
| SCHEMBL13128980 | 0.78 | L3MBTL1 (0.50) | SMN1; SMN2KDM4EL3MBTL1POLBMAPT | |
| SCHEMBL2740969 | 0.75 | CA1 (0.56) | PTK2BSMN1; SMN2L3MBTL1POLBMAPT | |
| SCHEMBL14161620 | 0.74 | POLB (0.60) | PTK2BSMN1; SMN2KDM4ETSHRL3MBTL1 | |
| SCHEMBL13128982 | 0.73 | CA1 (0.48) | L3MBTL1POLBMAPTGPR55MEN1 | |
| SCHEMBL13128921 | 0.73 | MAPT (0.51) | SMN1; SMN2KDM4EL3MBTL1POLBMAPT | |
| SCHEMBL2740961 | 0.71 | MEN1 (0.51) | PTK2BSMN1; SMN2KDM4ETSHRL3MBTL1 | |
| SCHEMBL13128919 | 0.70 | MEN1 (0.46) | PTK2BSMN1; SMN2TSHRMAPTMEN1 | |
| SCHEMBL15647634 | 0.69 | MAPT (0.60) | SMN1; SMN2KDM4EL3MBTL1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1932830-A1 | Sulfonamides and their use as a medicament | The Genetics Company, Inc. (CH) | 2008-06-18 | — | — | EP | disclosed |